205

Last update : 01/01/2019

EPHA - Observational study on the distribution of the various types of Atrial Fibrillation (AF)

Head : Vignal Franck, Sanofi Aventis

Main objective

Describe the distribution of the various types of Atrial Fibrillation (AF) in patients with an antecedent or in AF followed by a cardiologist in metropolitan France.

Inclusion criteria

• Patients seen in consultation by a cardiologist in general practice or at the hospital and followed by this cardiologist for at least 1 year
• Aged 18 years or older
• Having an antecedent or a documented AF (by ECG or Holter ECG) for at least one year, regardless of the rhythm on the day of inclusion
• Accepting to participate in the study and who have signed the consent agreement

Last update : 01/01/2019

INTENSIVE - Intensification of insulin therapy used in type-2 diabetes patients treated by the association of oral diabetes medication and basal insulin

Head : Vignal Franck, Sanofi Aventis

Version 1

206

Last update : 01/01/2019

INTENSIVE - Intensification of insulin therapy used in type-2 diabetes patients treated by the association of oral diabetes medication and basal insulin

Head : Vignal Franck, Sanofi Aventis

Main objective

Describe the evolution of HbA1c at 6 months under different therapeutic strategies for the intensification of insulin therapy used in type-2 diabetes patients treated by the association of oral diabetes medication and basal insulin requiring the adding of rapid insulin

Inclusion criteria

man or woman, over the age of 18 years, having type-2 diabetes meeting the criteria of the HAS: treated by the association of oral diabetes medication and basal insulin (semi slow or slow-acting) and requiring the adding of rapid insulin.

Last update : 01/01/2019

EGIR-RISC - Relationship between insulin sensitivity and cardiovascular disease

Head : Balkau Beverley
Ferrannini Ele

Version 3

207

Last update : 07/08/2025

EGIR-RISC - Relationship between insulin sensitivity and cardiovascular disease

Head : Balkau Beverley
Ferrannini Ele

Main objective

Main objective: study of insulin resistance and atherosclerosis, determinants of insulin resistance, its evolution on 9 years and consequences, diabetes, cardiovascular diseases and premature death.
Secondary objectives:
1. The evaluation of insulin resistance and its association with cardiovascular diseases
2. Identification of genetic and environmental factors linked to insulin resistance
3. The proposition of a model to identify insulin resistance

Inclusion criteria

- Aged between 30 and 60 years
- Good general health condition
- No symptoms of cardiovascular diseases
- blood pressure inferior to 170/90 mm Hg
- Total cholesterol inferior to 7,8 mmol/l
- Triglycerides levels inferior to 4,6 mmol/l
- Plasma glucose level (on an empty stomach and 2 hours after an oral glucose control) inferior to 7,0/11,1 mmol/l
- No treatment related to diabetes, hypertension or lipid disorders

Last update : 07/08/2025

- Cancer of The Oesophagus Associated with Tobacco Type, Alcohol use and Specific diet

Head : Launoy Guy, Cancers et populations

Version 1

208

Last update : 09/05/2017

- Cancer of The Oesophagus Associated with Tobacco Type, Alcohol use and Specific diet

Head : Launoy Guy, Cancers et populations

Main objective

To demonstrate that the risk of cancer of the oesophagus increases according to types of tobacco and alcohol use. To classify different types of tobacco and alcohol in accordance to risk of cancer of the oesophagus. To demonstrate certain dietary habits that increase the risk of cancer of the oesophagus.

Inclusion criteria

- Men - adult - under 85 years old - already presenting squamous carcinoma of the oesophagus

Last update : 09/05/2017

PRESAGE - Observationnal study on Postmenopausal woman

Head : Hébuterne Xavier, Eli Lilly France

Version 1

209

Last update : 01/01/2018

PRESAGE - Observationnal study on Postmenopausal woman

Head : Hébuterne Xavier, Eli Lilly France

Main objective

Primary objective: estimate the percentage of osteoporotic patients among postmenopausal patients with a mineral bone density measurement for diagnosis purposes and who can benefit from therapeutic recommendations according to French recommendations.
Secondary objectives: factors associated with osteoporosis, characteristics and care for patients

Inclusion criteria

Postmenopausal woman,
- Patient not treated for osteoporosis for at least one year (HRT, raloxifene, bisphosphonate, teriparatide, strontium ranelate),
- Patient coming for a bone densitometry for diagnosis purposes,
- Patient able to benefit from a therapeutic recommendation for the treatment of osteoporosis (osteopenic or osteoporotic patient with risk factors of fractures).

Last update : 01/01/2018

Episurvey Hepatite B - A cross-sectional, multicentre, epidemiological study of the drug management in hepatitis B

Head : Bregman Bruno, Bristol-Myers Squibb
Schmidely Nathalie, Bristol-Myers Squibb

Version 2

210

Last update : 09/05/2017

Episurvey Hepatite B - A cross-sectional, multicentre, epidemiological study of the drug management in hepatitis B

Head : Bregman Bruno, Bristol-Myers Squibb
Schmidely Nathalie, Bristol-Myers Squibb

Main objective

Describe the drug management of patients having chronic hepatitis B, in France, in 2006.

Inclusion criteria

M/F >=18 years, infected by the hepatitis B virus for at least 6 months, seen in outpatient clinic visit at expert centers for caring of hepatitis (Hepatitis Referenced University Hospitals, General Hospital Centres, community-based hepato-gastroenterologists) between 1 Jan. and 31 March 2006.

Last update : 09/05/2017