205

Last update : 01/01/2019

EPHA - Observational study on the distribution of the various types of Atrial Fibrillation (AF)

Head : Vignal Franck, Sanofi Aventis

Main objective

Describe the distribution of the various types of Atrial Fibrillation (AF) in patients with an antecedent or in AF followed by a cardiologist in metropolitan France.

Inclusion criteria

• Patients seen in consultation by a cardiologist in general practice or at the hospital and followed by this cardiologist for at least 1 year
• Aged 18 years or older
• Having an antecedent or a documented AF (by ECG or Holter ECG) for at least one year, regardless of the rhythm on the day of inclusion
• Accepting to participate in the study and who have signed the consent agreement

Last update : 01/01/2019

- Cancer of The Oesophagus Associated with Tobacco Type, Alcohol use and Specific diet

Head : Launoy Guy, Cancers et populations

Version 1

206

Last update : 09/05/2017

- Cancer of The Oesophagus Associated with Tobacco Type, Alcohol use and Specific diet

Head : Launoy Guy, Cancers et populations

Main objective

To demonstrate that the risk of cancer of the oesophagus increases according to types of tobacco and alcohol use. To classify different types of tobacco and alcohol in accordance to risk of cancer of the oesophagus. To demonstrate certain dietary habits that increase the risk of cancer of the oesophagus.

Inclusion criteria

- Men - adult - under 85 years old - already presenting squamous carcinoma of the oesophagus

Last update : 09/05/2017

INTENSIVE - Intensification of insulin therapy used in type-2 diabetes patients treated by the association of oral diabetes medication and basal insulin

Head : Vignal Franck, Sanofi Aventis

Version 1

207

Last update : 01/01/2019

INTENSIVE - Intensification of insulin therapy used in type-2 diabetes patients treated by the association of oral diabetes medication and basal insulin

Head : Vignal Franck, Sanofi Aventis

Main objective

Describe the evolution of HbA1c at 6 months under different therapeutic strategies for the intensification of insulin therapy used in type-2 diabetes patients treated by the association of oral diabetes medication and basal insulin requiring the adding of rapid insulin

Inclusion criteria

man or woman, over the age of 18 years, having type-2 diabetes meeting the criteria of the HAS: treated by the association of oral diabetes medication and basal insulin (semi slow or slow-acting) and requiring the adding of rapid insulin.

Last update : 01/01/2019

EGIR-RISC - Relationship between insulin sensitivity and cardiovascular disease

Head : Balkau Beverley
Ferrannini Ele

Version 3

208

Last update : 07/08/2025

EGIR-RISC - Relationship between insulin sensitivity and cardiovascular disease

Head : Balkau Beverley
Ferrannini Ele

Main objective

Main objective: study of insulin resistance and atherosclerosis, determinants of insulin resistance, its evolution on 9 years and consequences, diabetes, cardiovascular diseases and premature death.
Secondary objectives:
1. The evaluation of insulin resistance and its association with cardiovascular diseases
2. Identification of genetic and environmental factors linked to insulin resistance
3. The proposition of a model to identify insulin resistance

Inclusion criteria

- Aged between 30 and 60 years
- Good general health condition
- No symptoms of cardiovascular diseases
- blood pressure inferior to 170/90 mm Hg
- Total cholesterol inferior to 7,8 mmol/l
- Triglycerides levels inferior to 4,6 mmol/l
- Plasma glucose level (on an empty stomach and 2 hours after an oral glucose control) inferior to 7,0/11,1 mmol/l
- No treatment related to diabetes, hypertension or lipid disorders

Last update : 07/08/2025

SMP: first-time incarceration survey - Cohort of Detained Individuals: Mental Health Study

Head : Falissard Bruno, INSERM U669

Version 1

209

Last update : 09/05/2017

SMP: first-time incarceration survey - Cohort of Detained Individuals: Mental Health Study

Head : Falissard Bruno, INSERM U669

Main objective

Detailed description of this specific prison population and comparison with prevalent prison population (sub-sample of cross-sectional maisons d'arrêt survey); outcome of disorders at 1 month and qualitative analysis at 9 months.
(Initial aim: to determine specific factors for mental health deterioration in the short term. Aim is not achievable given the small number of individuals still present at the institution 9 months after their arrival).

Inclusion criteria

Individuals randomly drawn from available records at the Fresnes National Observation Centre and the diagnosis contained.

Last update : 09/05/2017

LYCOLL - Cross-sectional study of year-10 and year-11 students: influence of a change of environmental context on high-risk behaviours

Head : Binder Philippe

Version 1

210

Last update : 10/20/2017

LYCOLL - Cross-sectional study of year-10 and year-11 students: influence of a change of environmental context on high-risk behaviours

Head : Binder Philippe

Main objective

To study the influence of change in environmental context on the consumption of psychoactive products and on other high-risk behaviours, such as suicide. To describe the conditions of social and family life, education, health condition and associated behaviours.

Inclusion criteria

Students in year 10 and 11 assimilated in Charente-Maritime.

Last update : 10/20/2017